Macroconnection ( Thompson & Swanson, 2010 ) : A connection between two gray matter regions; p. 15239. At this level of analysis gray matter regions are treated as black box nodes, disregarding their composition of neuron types (Bota & Swanson, 2007) and local connections. That is, macroconnections are described to and from particular gray matter regions, disregarding local connections within the gray matter regions. In normal, healthy animals global macroconnection patterns are genetically hardwired.