Node : The site of origin or of termination of a connection at the level of a gray matter region (macronode), neuron type (Bota & Swanson, 2007) (mesonode), or individual neuron (Waldeyer, 1891) (micronode). Nodal masses of gray matter were described systematically as long ago as Meynert (1872, p. 654).

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Center : This term has multiple connotations. It is often used to indicate the site of a particular function, or as a rough synonym for node. It was used essentially in the latter sense as far back as Manfridi (1490; see Singer 1917, p. 108) and Bartholin (1662, p. 142). Of course center can also refer to the middle point of an object.