Topographic macroarchitecture of nervous system ( Swanson & Bota, 2010 ) : One of two common orthogonal ways to describe completely the nervous system (Monro, 1783). Topography here deals with the accurate macroscopic (gross anatomical) delineation and description of major locations in the nervous system, in contrast to the subsystems description of nervous system that deals with the microscopic-histological organization of gray matter regions and white matter tracts-and the connections they form. A topographic location in the nervous system, like the midbrain (Baer, 1837), is usually a heterogeneous mixture of components, including parts of the circulatory system, meninges (Edwin Smith Surgical Papyrus, c1700 BC), ventricles-subarachnoid space, gray matter regions, and white matter tracts.